商品介绍
HDAC-1 Antibody
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Product Description | The affinity purified rabbit polyclonal anti-HDAC1 antibody is developed using the C-terminal peptide of human histone deacetylase 1. It could be used for detection and isolation of HDAC-1. |  Western blot analysis of Jurkat cell lysate (3, 10 and 30 µg) with CN0801. | |
Species | Rabbit | ||
Formulation | 0.25 mg/mL in TBS, 50% glycerol, 0.01% NaN3 | ||
Immunogen | Human HDAC1 (protein code: Q13547) C-terminal peptide KLH conjugates | ||
Purification | The antibody was purified with antigen-specific immunoaffinity chromatography. | ||
Specificity | The antibody recognizes human HDAC-1. It may cross-react with HDAC-1 from other species. | ||
Applications | ELISA; WB (1:1000); IP | ||
Scientific Description | Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from the ε-N-acetyl lysine amino acid on histones or other proteins. Its action is opposite to that of histone acetyltransferase. HDAC proteins are found in three groups, the first two groups belong to the classical HDACs whose activities are inhibited by trichostatin A (TSA). The third group is a family of NAD+- dependent proteins unaffected by TSA. Homologues to all three groups are found in yeast: reduced potassium dependency 3 (Rpd3) corresponding to class 1, histone deacetylase 1 (hda1) to class 2 and silent information regulator 2 (Sir 2) corresponding to class 3. | ||
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored. | ||
品牌介绍
加拿大ImmuneChem Pharmaceuticals, Inc. www.immunechem.comImmuneChem是一家由活跃在美国、加拿大生物科技前沿的华人科学家和留学生创建的。其核心技术及研发平台由加拿大ICP免疫公司和美国、加拿大数家拥有一流科学家和设备的实验室提供，并均已获得了技术持有人（公司）的授权。 主营产品公司提供以下产品： 1.细胞信号传导通路抗体，翻译后修饰抗体，细胞凋亡相关抗体，非放射性蛋白激酶测试盒，亲和填料； 2.磷酸化抗体，非磷酸化抗体，甲基化抗体，乙酰化
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