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Product Description | IRF4 is a transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. |
Species | Rabbit |
Formulation | 250 µg/mL in 0.1 N Tris-acetate, pH7.0, 0.01% NaN3, and 50%glycerol |
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if properly stored. |
Immunogen | Human IRF4 peptide-KLH conjugates |
Purification | The antibody was affinity purified with Human IRF4 peptide on Agarose. |
Applications | ELISA,WB, IP. |
Specificity | The antibody recognizes IRF4 at around 50 kd. |
Scientific Description | IRF4 also called lymphocyte-specific interferon regulatory factor. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. |
Product Specific References | 1.Biochem. J. 1989.257: 535-540. |
加拿大ImmuneChem Pharmaceuticals, Inc. www.immunechem.comImmuneChem是一家由活跃在美国、加拿大生物科技前沿的华人科学家和留学生创建的。其核心技术及研发平台由加拿大ICP免疫公司和美国、加拿大数家拥有一流科学家和设备的实验室提供,并均已获得了技术持有人(公司)的授权。 主营产品公司提供以下产品: 1.细胞信号传导通路抗体,翻译后修饰抗体,细胞凋亡相关抗体,非放射性蛋白激酶测试盒,亲和填料; 2.磷酸化抗体,非磷酸化抗体,甲基化抗体,乙酰化