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Product Description | ING1 is a tumour suppressor. Affinity purified rabbit polyclonal anti-p33 ING1 is developed with the N-terminal peptide based on mouse p33 ING1, the identical sequence of human p33 ING1. | A:Cell expressed-flag p33 ING1, blot with Ab from other commercial source.B:Cell expressed p33 ING1, blot with Ab from other commercial source.C: Cell expressed-flag p33 ING1, blot with Ab ICP0280.D: Cell expressed p33 ING1, blot with Ab ICP0280. | |
Species | Rabbit | ||
Formulation | 250 µg/mL in TBS, 50% glycerol, 0.01% NaN3 | ||
Immunogen | Mouse p33 ING1 N-terminal peptide-KLH conjugates | ||
Purification | The antibody was affinity purified with p33 ING C-terminal peptide on agarose. | ||
Specificity | The antibody recognizes p33 ING1 of human and mouse. There are no cross reactions with other members of the ING family. | ||
Applications | ELISA (0.5 µg/mL); WB (1 µg/mL); IFC (1:50) | ||
Scientific Description | p33 (ING1) is a new growth inhibitor candidate for a tumour suppressor gene. p33 (ING1) cooperates with p53 and down-regulates cell growth by activating transcription from the p21/WAF1 promoter although there is no sequence similarity between p33 (ING1) and p53. | ||
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly. | ||
Product Specific References | 1. Cancer Lett. 1999. 147: 157-162. doi:10.1016/SD3D4-3835(99)00288-8 |
加拿大ImmuneChem Pharmaceuticals, Inc. www.immunechem.comImmuneChem是一家由活跃在美国、加拿大生物科技前沿的华人科学家和留学生创建的。其核心技术及研发平台由加拿大ICP免疫公司和美国、加拿大数家拥有一流科学家和设备的实验室提供,并均已获得了技术持有人(公司)的授权。 主营产品公司提供以下产品: 1.细胞信号传导通路抗体,翻译后修饰抗体,细胞凋亡相关抗体,非放射性蛋白激酶测试盒,亲和填料; 2.磷酸化抗体,非磷酸化抗体,甲基化抗体,乙酰化