Mouse Anti-Thyroxine Antibody
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| Product Description | This antibody was developed using Tthyroxine (T4) linked to the immunogenic carrier protein -KLH conjugates as the immunogen, The T4-specific antibodies wasaffinity purified with antigen-specific affinity chromatography The antibody could be utilized for detection, quantization and affinity isolation and purification of estradiol in biofluid. | Competitive ELISA  Immobilization: 0.5 ug/mL 100uL/well of Anti T4 (ICP1398) antibodies at 37C for 30min. Detection: T4 HRP (250 ng/mL, 100uL/well) at 37C for 30 min. Competitive Inhibition: both T4 and T3 range from 0.25 ng/mL to 50 ng/mL.  Structure of the T4 Immunogen | |
| Species | Mouse | ||
| Formulation | 250 µg/mL in PBS with 50% glycerol | ||
| Immunogen | T4-linked KLH protein conjugates | ||
| Purification | Antigen-specific immune-affinity chromatography | ||
| Specificity | The antibody recognizes free thyroxine (T4) and conjugated thyroxine to protein via its alpha amine group. Slightly cross reacted with T3 | ||
| Applications | Quantitative ELISA: IC50=1-5 ng/mL Immunoaffinity Chromatography | ||
| Scientific Description | Thyroxine, also called 3,5,3′,5′-tetraiodothyronine, or T4,one of the two major hormones secreted by thethyroid gland (the other is triiodothyronine). Thyroxine’s principal function is to stimulate the consumption of oxygen and thus the metabolism of all cells and tissues in the body. Thyroxine is formed by the molecular addition of iodine to the amino acid tyrosine while the latter is bound to the protein thyroglobulin. Excessive secretion of thyroxine in the body is known as hyperthyroidism, and the deficient secretion of it is called hypothyroidism | ||
| Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored. |
加拿大ImmuneChem Pharmaceuticals, Inc. www.immunechem.comImmuneChem是一家由活跃在美国、加拿大生物科技前沿的华人科学家和留学生创建的。其核心技术及研发平台由加拿大ICP免疫公司和美国、加拿大数家拥有一流科学家和设备的实验室提供，并均已获得了技术持有人（公司）的授权。 主营产品公司提供以下产品： 1.细胞信号传导通路抗体，翻译后修饰抗体，细胞凋亡相关抗体，非放射性蛋白激酶测试盒，亲和填料； 2.磷酸化抗体，非磷酸化抗体，甲基化抗体，乙酰化
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